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To investigate the effects of sulindac on neuronal apoptosis and autophagy in zebrafish, a red fluorescent protein (RFP)-tagged Lc3 (RFP-Lc3) plasmid was injected to mark the magnitude of autophagic flux, and AO staining was used to mark apoptotic cells 45

During the course of the study, there was no change to the therapeutic regime other than the introduction of parenteral cobalamin supplementation

Introduction CD38 was discovered in 1980 by E B signaling pathway in non-Hodgkin's lymphoma B-cell lines: role in sensitization to chemotherapeutic drug-induced apoptosis